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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span style='color:#1F497D'>I was able to solve both the OME-TIFF export speed problem and the ModuloAlongT problem by using a hybrid approach: using the LOCI tools to create the OME-XML metadata, but then using the MATLAB Tiff() class for the actual OME-TIFF writing. I tried this because of information on the forums that the MicroManager saving of OME-TIFFs was faster than the Bio-formats code.<o:p></o:p></span></p><p class=MsoNormal><span style='color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='color:#1F497D'>I’ve enclosed the MATLAB code that I used for this hybrid approach, in case anyone is interested. The first section is a little parochial (using our local data objects), but most of the code should be re-usable. This code wrote a medium-sized set of data in 1.3 seconds, compared with 89 seconds for using only calls to LOCI for the writing; although both cases had BigTiff and LZW compression set, the file using the hybrid approach was also about ~3x smaller for some reason (1.7 GB vs 5.3 GB; the 1.7 GB is essentially the same size as the MATLAB .mat file version of the same data). Both versions of the file are readable using the Bio-Formats importer in Fiji.<o:p></o:p></span></p><p class=MsoNormal><span style='color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='color:#1F497D'>I have used simpler metadata notations for the TiffData entries; they just include the starting IFD number and the number of planes.<o:p></o:p></span></p><p class=MsoNormal><span style='color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='color:#1F497D'>This also solved the problem with the ModuloAlongT SA metadata (which apparently became corrupted during or after the writer.saveBytes calls).<o:p></o:p></span></p><p class=MsoNormal><span style='color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='color:#1F497D'>gary<o:p></o:p></span></p></div></body></html>