<html><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; "><div><font class="Apple-style-span" face="Verdana, Helvetica, Arial">Dear All,</font></div><div><font class="Apple-style-span" face="Verdana, Helvetica, Arial"><br></font></div><div><font class="Apple-style-span" face="Verdana, Helvetica, Arial">Please can I draw your attention to tomorrow's seminar with Marek Cyrklaff on cryo-electron tomography at 12 noon in the WTB seminar room. This promises to be an excellent talk from a recognised expert in cryo-electron tomography and should be of interest to all of you. And if that's not good enough... we will be upgrading one of our microscopes for tomography later in the year, so this is an excellent opportunity to find out a little more about how this technique may be relevant to your own research.</font></div><div><font class="Apple-style-span" face="Verdana, Helvetica, Arial"><br></font></div><div><font class="Apple-style-span" face="Verdana, Helvetica, Arial">Cheers,</font></div><div><font class="Apple-style-span" face="Verdana, Helvetica, Arial">Sam</font></div><div><font class="Apple-style-span" face="Verdana, Helvetica, Arial"><br></font></div><div><font class="Apple-style-span" face="Verdana, Helvetica, Arial" size="3"><span class="Apple-style-span" style="font-size: 12px;"><span class="Apple-style-span" style="font-size: medium;"><br></span></span></font></div><div><font face="Verdana, Helvetica, Arial"><span style="font-size:12.0px"> Joint Seminar CBI Division and Central Microscopy <br> <br> Dr Marek Cyrklaff <br> University of Heidelberg<br> <br> "Cryo-electron tomography of whole cells"<br> <br> Tuesday 8th June<br> <br> 12noon<br> <br> WTB Seminar Rooms (Front and Back)<br> <br> Host John Lucocq <br> <br> Everybody Welcome!<br> <br> Marek is an expert in cryoelectron tomography, which provides 3D-nanometre<br> resolution imaging of rapidly frozen intact cells and molecular assemblies<br> at near-native state. This is, and will be, THE definitive benchmark<br> technique for analysing cell and molecular structures in situ, superseding<br> traditional “text book” and other cryo- EM methods. Marek has contributed to<br> the pioneering development of this key method by means of his analysis of<br> intact whole cells including human parasites, bacteria and parts mammalian<br> cells (e.g. neuron synapses) - producing the first images of whole<br> plasmodium sporozoites and the borreliosis (Lyme disease) spirochete. His<br> talk will be of interest to anyone interested in “true-to-life”<br> morphofunctional relationships in intact cells.</span></font></div></body></html>